How Far Can Raman Spectroscopy Push Trace Gas Detection? For scientists working with trace gases, the challenge is often not identifying what to measure. The challenge is reliably detecting it at ever-lower concentrations. As concentrations fall, Raman spectroscopy faces a fundamental limitation: the Raman effect is inherently weak. IS-Instruments' Notus gas Raman technology addresses this […]

Latest test results from IS-Instruments’ Notus gas Raman system demonstrate rapid measurement of multiple gases at concentrations as low as 5 ppm, using a single instrument with no adjustments between measurements. Results for methane and ethylene also indicate potential limits of detection in the hundreds of ppb with the current setup. Gas Raman spectroscopy offers […]

Bioprocesses are dynamic environments. As cell cultures grow and express the biological products required for medicines and vaccines, conditions within the bioreactor continually change. Understanding those changes in real time requires analytical technologies that can operate within the process itself. In-line Process Analytical Technology (PAT) can provide manufacturers with real-time information about changing conditions within […]

Developing a robust laser delivery solution for pharmaceutical process monitoring Hollow-core fibre (HCF) is opening new possibilities for UV Raman spectroscopy. Unlike conventional optical fibres, which transmit light through solid glass, HCF guides light predominantly through air. This significantly reduces UV-induced degradation in standard silica fibres, making HCF an attractive option for applications requiring reliable, […]

In continuous gas-blending environments, the challenge is often not generating the correct mixture but verifying the composition quickly enough to respond to process deviations in real time. In these environments, even small deviations in gas composition can have significant consequences, affecting product quality, safety, and regulatory compliance. Traditionally, gas blending processes rely on mass flow […]

As ISI's NOTUS gas Raman system enters its final testing stages, recent measurements highlight the analytical capabilities of gas Raman spectroscopy for rapid gas identification. One of the main advantages of Raman spectroscopy is its ability to detect multiple gas species quickly. It achieves this without needing consumables or complicated sample preparation. Consequently, the technique […]

Last week, IS-Instruments (ISI) was pleased to welcome local MP Tom Tugendhat to our Tonbridge facility. During the visit, he met members of the team and learned more about the advanced Raman spectroscopic technologies being developed within his constituency. He had the opportunity to see advanced Raman spectroscopy in action! Additionally, he got to meet […]

On 12 April, IS-Instruments team member Jessica Gabb will take on the London Landmarks Half Marathon (LLHM). She's raising funds for Macmillan Cancer Support through her JustGiving page. This isn’t just a run or part of a personal challenge. This is a cause that matters to her and to the ISI wider family. Why the […]

Fusion energy promises to be a safe, low-carbon and sustainable part of the world’s future energy supply. In recent years, progress in the UK and internationally has demonstrated this potential. At the same time, it has highlighted the significant scientific and engineering challenges that still remain. One of these challenges is developing accurate tritium measurement […]