• Behind the scenes: the software engineering that keeps scientific instruments working 21/10/2026
    From modernising instrument control software to improving user experience, 2026 has been a year of significant development at IS-Instruments. Much of that work will never be noticed by the people using our instruments, and that's rather the point. In a theatre production, the audience focuses on the actors and the performance. Behind the scenes, a […]
    Sarah Marsh-Collings
  • Advancing Hydrogen Isotope Analysis: Notus Demonstrates Simultaneous Detection of All Six Isotopologues 13/10/2026
    New results from the UKAEA-funded GRADE 3 programme demonstrate the potential of low-power Raman spectroscopy for hydrogen isotope analysis in fusion applications. Accurate hydrogen isotope analysis is essential for developing fusion energy. As the industry moves towards commercial-scale operation, reliable measurement technologies will become increasingly important. These technologies could support fuel-cycle management, process development and […]
    Sarah Marsh-Collings
  • How Far Can Raman Spectroscopy Push Trace Gas Detection? 22/09/2026
    How Far Can Raman Spectroscopy Push Trace Gas Detection? For scientists working with trace gases, the challenge is often not identifying what to measure. The challenge is reliably detecting it at ever-lower concentrations. As concentrations fall, Raman spectroscopy faces a fundamental limitation: the Raman effect is inherently weak. IS-Instruments' Notus gas Raman technology addresses this […]
    Sarah Marsh-Collings
  • Notus Demonstrates Low-ppm Multi-Gas Detection in Latest Tests 15/09/2026
    Latest test results from IS-Instruments’ Notus gas Raman system demonstrate rapid measurement of multiple gases at concentrations as low as 5 ppm, using a single instrument with no adjustments between measurements. Results for methane and ethylene also indicate potential limits of detection in the hundreds of ppb with the current setup. Gas Raman spectroscopy offers […]
    Sarah Marsh-Collings
  • Developing Deep-UV Raman Probes for In-Line Process Analytical Technology 07/09/2026
    Bioprocesses are dynamic environments. As cell cultures grow and express the biological products required for medicines and vaccines, conditions within the bioreactor continually change. Understanding those changes in real time requires analytical technologies that can operate within the process itself. In-line Process Analytical Technology (PAT) can provide manufacturers with real-time information about changing conditions within […]
    Sarah Marsh-Collings
  • Engineering Hollow-Core Fibre for Real-World UV Raman Applications 30/07/2026
    Developing a robust laser delivery solution for pharmaceutical process monitoring Hollow-core fibre (HCF) is opening new possibilities for UV Raman spectroscopy. Unlike conventional optical fibres, which transmit light through solid glass, HCF guides light predominantly through air. This significantly reduces UV-induced degradation in standard silica fibres, making HCF an attractive option for applications requiring reliable, […]
    Sarah Marsh-Collings
  • Real-Time Gas Blend Monitoring: Moving Beyond Batch Verification 12/05/2026
    In continuous gas-blending environments, the challenge is often not generating the correct mixture but verifying the composition quickly enough to respond to process deviations in real time. In these environments, even small deviations in gas composition can have significant consequences, affecting product quality, safety, and regulatory compliance. Traditionally, gas blending processes rely on mass flow […]
    Sarah Marsh-Collings
  • Rapid Multi-Gas Detection Using Raman Spectroscopy 11/03/2026
    As ISI's NOTUS gas Raman system enters its final testing stages, recent measurements highlight the analytical capabilities of gas Raman spectroscopy for rapid gas identification. One of the main advantages of Raman spectroscopy is its ability to detect multiple gas species quickly. It achieves this without needing consumables or complicated sample preparation. Consequently, the technique […]
    Sarah Marsh-Collings
  • Tom Tugendhat MP Visits IS-Instruments to See Advanced Raman Spectroscopy in Action 05/03/2026
    Last week, IS-Instruments (ISI) was pleased to welcome local MP Tom Tugendhat to our Tonbridge facility. During the visit, he met members of the team and learned more about the advanced Raman spectroscopic technologies being developed within his constituency. He had the opportunity to see advanced Raman spectroscopy in action! Additionally, he got to meet […]
    Sarah Marsh-Collings