In recent years spatially offset and transmission Raman measurements have gained popularity in a variety of sectors, including the pharmaceutical and forensics industries. The key advantage of transmission Raman in particular is that it provides a bulk measurement of the sample and is therefore resistant to false returns

The HES2000 spectrometer offered by ISI can capture the light from a 1 mm input fibre, requires no slit whilst maintaining a high level of spectral resolution (3 cm-1 per measurement bin). An experimental comparison campaign between a HES2000 instrument and a market-leading fibre coupled Czerny Turner instrument to make Transmission Raman measurements of a 5 mm thick paracetamol tablet has been conducted.

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